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The visible change is driven mainly by the magnitude and pace of weight loss
These mechanisms are complementary
doi: 10.1021/JM401992E 53 BarnettA
Due to the exhaustion of cellular and extracellular GSH caused by numerous GSH-consuming pathways the severe inflammation and oxidative stress triggered by the viral infection steals GSH from crucial functions like NO-dependent vasodilatation, disallowing the patient of being protected from an inflammation that can become fatal
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